Monterrey vs. Santos Laguna Prediction, Match Preview and Betting Tips, 28 September 2025

Mark your calendars for an early kick-off on 28 September 2025 as Monterrey takes on Santos Laguna in an engaging fixture of Liga MX at the Estadio BBVA. Monterrey, currently 3rd on the table, will be looking to capitalize on their strong form of 3 wins, 1 draw, and 1 loss in their last five matches. Managed by Nicolás Sánchez, they boast an excellent home record, having scored in 100% of their home games this season.

Santos Laguna, on the other hand, struggle in 13th place, with just a single win in their last five encounters. Coached by Juan Pablo Rodríguez, they come into this clash with low confidence but will aim for a splash against a formidable opponent.

Historically, Monterrey has dominated their head-to-head battles with Santos Laguna, which further cements our recommended bet: a home win for Monterrey.

Expect goals from top scorer German Berterame and a typical solid defensive performance led by veteran Sergio Ramos. Don’t miss this critical encounter as it could shape the upcoming rounds in Liga MX!

Monterrey vs Santos Laguna Prediction & Betting tip

It’s hard to look past Monterrey for this one. With their superior form, strong home record, and historical dominance over Santos Laguna, the smart money is on a home win.

• Current Form and Standing: Monterrey is in excellent form, sitting 3rd in Liga MX compared to Santos Laguna’s 13th spot.
• Scoring Ability: Monterrey has scored 12 goals in their last 5 matches, highlighting their offensive firepower.
• Head-to-Head Dominance: Monterrey has won all of their last 5 encounters against Santos Laguna, often by significant margins.

Within the context of this upcoming fixture, these factors make Monterrey the clear bookmaker favourite. Look out for goals from their top scorer German Berterame and a solid display from Sergio Ramos in defence.

Monterrey vs Santos Laguna Odds

This Liga MX matchup between Monterrey and Santos Laguna presents compelling odds to bettors. Monterrey, being the bookmaker favourite, is expected to dominate the game given their superior form and track record. They come into this match with a favourable home record and a robust recent performance, making them the go-to option for many.

Monterrey’s 1.30 odds for a win reflect their recent dominance and strong form, including 3 wins in their last 5 matches. A draw is less likely but offers higher odds, while a win for Santos Laguna, given at 7.78, seems an absolute long shot as they struggle in the league. Be sure to consider these odds while making your bet and keep in mind Monterrey’s key players like German Berterame and Sergio Ramos.

Monterrey Team Analysis

Monterrey Recent Performance

Monterrey’s recent form has been a rollercoaster, encapsulated in their last five matches: 3 wins, 1 draw, and 1 loss (WWWDL). Despite a staggering 6-2 loss against Toluca, they have shown excellent form overall, highlighted by significant victories over Puebla (4-2) and Necaxa (3-0).

On average, Monterrey has scored 2.40 goals per game in these matches, underlining their potent attacking capabilities. They have managed to maintain two clean sheets in their last five games, driven by a solid defensive performance from the likes of veteran Sergio Ramos.

Their offensive prowess is spearheaded by German Berterame, who has bagged 6 goals this season and remains a constant threat in front of goal. With an impressive home record, scoring in 100% of home fixtures, Monterrey looks set to continue their good run in Liga MX.

Monterrey Key Players

When it comes to key players for Monterrey, the spotlight primarily falls on their top scorer, German Berterame, who has netted 6 goals this season. His partnership with playmaker Jesus Manuel Corona, who often sparks the attack from the left, will be crucial in breaking down Santos Laguna’s defence.

In midfield, the creativity of Sergio Canales and Oliver Torres offers the team multiple avenues to create scoring opportunities. Defensively, veteran Sergio Ramos commands the backline with his experience, offering both leadership and stability.

Expect Monterrey to line up as follows:

• Goalkeeper: Santiago Mele
• Defenders: Erick Aguirre, Sergio Ramos, Stefan Medina, Luis Ricardo Reyes
• Midfielders: Jorge Rodriguez, Oliver Torres, Sergio Canales, Jesus Manuel Corona, Fidel Ambriz
• Forward: German Berterame

This mix of attacking flair and defensive solidity makes Monterrey a well-rounded team difficult to beat on any given day.

Monterrey Suspensions & Injuries

Good news for Monterrey fans! Heading into their clash with Santos Laguna, Nicolás Sánchez’s side has a clean bill of health, with no injuries or suspensions to report.

This lack of absences allows Monterrey to field their strongest line-up, boasting stars such as German Berterame and Sergio Canales. The full squad availability ensures that Sánchez can employ his ideal tactics and strategies without any forced adjustments due to missing players.

With a solid and consistent first XI, Monterrey will look to exploit Santos Laguna’s defensive vulnerabilities and maintain their impressive home scoring record. The team’s full strength sets the stage for a potentially dominant performance at the Estadio BBVA.

Monterrey Tactics and Formation

For their upcoming clash against Santos Laguna, Monterrey is expected to stick to their tried-and-tested 4-2-3-1 formation.

Tactical Breakdown:

• Formation: 4-2-3-1
• Key Forward: German Berterame
• Creative Midfielders: Sergio Canales and Oliver Torres, pivotal in supply and playmaking.
• Defensive Line: Led by experienced Sergio Ramos, stabilised by Stefan Medina and backed by goalie Santiago Mele.
• Wing Play: Jesus Manuel Corona on the left and Erick Aguirre on the right, both crucial in wide attacks and defensive transitions.
• Notable Strategy: Quick transitions from defence to attack, leveraging wide areas and central playmaking to create scoring opportunities.

Their attacking philosophy, combined with a disciplined defensive setup, aims to dominate possession while exploiting spaces left by the opposition.

Santos Laguna Team Analysis

Santos Laguna Recent Performance

Santos Laguna has struggled to find consistency, as reflected in their last five matches: 1 win, 1 draw, and 3 losses (LLDLW). They managed a narrow 1-0 victory over Tijuana, but suffered a heavy 4-1 defeat at the hands of Atletico de San Luis and a disappointing 2-1 loss to FC Juarez.

On average, the team has scored 1.00 goal per game over these five matches, emphasising their issues in finding the back of the net. Defensively, they’ve managed just one clean sheet, conceding an average of 1.7 goals per game throughout the season.

Led by top scorer Cristian Dajome, who has 4 goals, Santos Laguna will need a significant upturn in form to challenge the high-flying Monterrey. With a tough run ahead, including an upcoming match against CF America, Santos Laguna remains in desperate need of points to improve their mid-table standing.

Santos Laguna Key Players

Santos Laguna will heavily rely on their key players to make an impact against a strong Monterrey side. Leading the charge is their top scorer, Cristian Dajome, who has netted 4 goals this season. Dajome’s ability to find space and finish will be crucial in a match where Santos Laguna may have limited opportunities.

Salvador Mariscal is another pivotal figure, orchestrating play from the midfield and providing the creative spark needed to unlock Monterrey’s defence. Defensively, goalkeeper Carlos Acevedo will be vital, tasked with keeping Monterrey’s potent attack at bay.

Expect the following lineup for Santos Laguna:

• Goalkeeper: Carlos Acevedo
• Defenders: Jose Abella, Kevin Balanta, Jonathan Pérez, Bruno Amione
• Midfielders: Javier Guemez, Kevin Palacios, Ramiro Sordo, Salvador Mariscal, Jordan Carrillo
• Forward: Jesús Ocejo

Their performance will hinge on coordinated team play and strategic use of key players to exploit any weaknesses in Monterrey’s setup.

Santos Laguna Suspensions & Injuries

Santos Laguna will be missing one crucial player due to suspension for their clash against Monterrey. Bruno Barticciotto is sidelined after accruing a yellow/red card, leaving him banned for one match. His absence will undoubtedly affect the defensive solidity of Santos Laguna, as Barticciotto has been a key figure in their backline.

With an already struggling defensive record, losing Barticciotto makes the task even harder for Juan Pablo Rodríguez’s side. This gap in their defence could be a significant factor, making it easier for Monterrey’s attack, led by German Berterame, to exploit.

Apart from this suspension, there are no reported injuries. This situation allows Santos Laguna to field a reasonably strong team in an attempt to challenge Monterrey, despite the missing defensive cog.

Santos Laguna Tactics and Formation

For the upcoming match against Monterrey, Santos Laguna is expected to adopt a 4-2-3-1 formation, a setup they have used multiple times in recent games.

Tactical Breakdown:

• Formation: 4-2-3-1
• Key Forward: Jesús Ocejo, tasked with converting attacking opportunities into goals.
• Midfield Setup: Salvador Mariscal will play a pivotal role in linking defense and attack, while Javier Guemez and Kevin Palacios will focus on breaking down Monterrey’s play.
• Defensive Line: With Bruno Barticciotto suspended, Jonathan Pérez and Kevin Balanta will need to step up to solidify the backline.
• Goalkeeper: Carlos Acevedo, crucial for making key saves and organising the defence.

Santos Laguna’s strategy will likely revolve around a compact defensive setup to stymie Monterrey’s attack, while looking to hit on the counter through quick transitions and utilising the wings to create scoring chances.

Monterrey vs Santos Laguna Head-to-Head Statistics

In the last five meetings between Monterrey and Santos Laguna, Monterrey has shown clear dominance, securing victories in all encounters. Here’s a closer look at their recent head-to-head record:

• 2025-03-03 Liga MX Clausura: Monterrey 4 – 2 Santos Laguna
• 2024-09-15 Liga MX Apertura: Santos Laguna 0 – 2 Monterrey
• 2024-01-22 Liga MX Clausura: Santos Laguna 0 – 2 Monterrey
• 2023-11-09 Liga MX Apertura: Monterrey 3 – 0 Santos Laguna
• 2023-05-14 Liga MX Clausura Playoff: Monterrey 2 – 0 Santos Laguna

Monterrey has consistently outperformed Santos Laguna in these matches, both offensively and defensively. With a combined scoreline of 13-2 across these five fixtures, it’s evident why Monterrey enters this game as the bookmaker favourite.

This strong head-to-head record, combined with Monterrey’s current form and home advantage, suggests they are well-positioned to continue their winning streak against Santos Laguna.

Odds accurate as of 26/09/2025 02:03 and are subject to change. Please always check the odds before placing your bets with any bookmaker.