This is going to be a tight game as the two players here would do all possible best to frustrate the plans of each other to win. Thus I see the possibility of the game ending in two sets as Ekaterina would be more daring here to win the game.
A deceptively tough opponent, Cocciaretto gets to every ball on clay and she has enough power to get a good first serve in and some important winners. Alexandrova will hit with the best of them, but when she faces a player who is counter to how she usually wants to play, she can often break down.
I will also look at the over, as I've seen enough Alexandrova matches to know that when those nerves and doubts creep in, the serve percentage starts to go down and the errors start to go up. Cocciaretto is good on clay and actually has a deceptively good serve as well, so I could see some longer sets here as well.
E. Cocciaretto is 89th while E. Alexandrova is 20th in the WTA-Tour these days. The Italian Cocciaretto is coming off a good straight set win over Townsend most recently. Meanwhile Alexandrova is coming off a straight set win over Bronzetti in the first round. I recommend a bet on first set E. Coacciaretto to win.