Club Universidad Nacional vs. CD Guadalajara Prediction, Match Preview and Betting Tips, 6 October 2025

As Liga MX action heats up, the clash between 10th-placed Club Universidad Nacional (Pumas) and 9th-placed CD Guadalajara (Chivas) promises to be crucial. With just a single point separating them, both teams are eyeing a vital win to climb the standings.

Home advantage tips the scale slightly towards Pumas, who have shown resilience at the Olimpico Universitario. Their recent form, however, has been inconsistent, highlighted by a heavy 4-1 defeat to CF America but also a 4-1 away win against Mazatlan.

Chivas, led by top scorer Armando Gonzalez, have been similarly unpredictable. Their away win at Puebla and a strong home victory over Necaxa demonstrate their capability, although they suffer from several injuries.

Backing Pumas to win seems a smart bet, especially with bookmakers favouring them and considering their better defensive record at home. Both sides’ erratic forms make Pumas’ local crowd support a pivotal factor in the match.

Club Universidad Nacional vs CD Guadalajara Prediction & Betting Tip

Club Universidad Nacional vs CD Guadalajara Prediction
Betting tip
Pumas UNAM to Win – Odds: 2.23

Pumas UNAM enters this matchup with a slight home advantage, sitting just one point behind Chivas in the standings. Despite both teams showing inconsistency, Pumas’ home record offers optimism. Although their recent head-to-head history favours CD Guadalajara, Pumas’ solid performances at the Estadio Olímpico Universitario strike a positive balance.

• Pumas UNAM’s stronger home form and the crowd support at the Estadio Olímpico Universitario are essential factors.
• Chivas have been inconsistent on the road, and their injury list could weaken their performance.
• Both teams have been unpredictable, making home advantage a crucial edge for Pumas.

Backing Pumas UNAM to win is a sensible bet, especially given their solid home performances and the bookmakers’ odds favouring them.

Club Universidad Nacional vs CD Guadalajara Odds

In this hotly anticipated Liga MX encounter, betting markets slightly favour Club Universidad Nacional (Pumas) over CD Guadalajara (Chivas). The odds reflect a tight contest given their close standings in the league, with Pumas sitting just one point and one place behind Chivas.

Club Universidad Nacional vs CD Guadalajara Betting Odds
Bet	Odds
Pumas UNAM to Win	2.23
Draw	3.23
Chivas to Win	3.05

Backing Pumas seems a strategic choice. Their home form has been solid, and playing at the Estadio Olímpico Universitario offers a tangible edge. Additionally, Chivas’ inconsistency on the road and injury concerns could tilt the scales in Pumas’ favour. Though the head-to-head history is tight, the odds suggest a narrow advantage for the home team.

Club Universidad Nacional Team Analysis

Club Universidad Nacional Recent Performance WWDLL

Club Universidad Nacional has shown mixed form in their recent outings:

• CF America 4-1 Club Universidad Nacional (2025-09-28)
• FC Juarez 3-1 Club Universidad Nacional (2025-09-24)
• Club Universidad Nacional 1-1 Tigres (2025-09-21)
• Mazatlan FC 1-4 Club Universidad Nacional (2025-09-13)
• Club Universidad Nacional 1-0 Atlas (2025-08-31)
  Recent Form: WWDLL

In the last five matches, Pumas have had varied success, securing two wins, one draw, and two losses. They have averaged 1.60 goals per game and managed to keep just one clean sheet during this period. This inconsistent form highlights the challenge they face, but it’s worth noting their 4-1 away victory against Mazatlan showcased their potential on their day.

Despite conceding several goals, Pumas’ ability to score, particularly in the latter stages of matches, remains a positive takeaway for their upcoming fixture against Chivas.

Club Universidad Nacional Key Players

As Club Universidad Nacional prepares for this crucial match, key players will need to step up to secure a vital victory. Given Guillermo Martinez’s foot injury, much of the attacking responsibility shifts to José Juan Macías, who’s expected to lead the line.

Jorge Ruvalcaba, the team’s current top scorer with 4 goals, will also be crucial, operating from the left wing. Another pivotal player is Pedro Vite, whose creativity and pace down the right flank could prove decisive. Midfield general Adalberto Carrasquilla will be tasked with controlling the tempo, providing both defensive cover and link-up play to the attack.

Expected lineup for Club Universidad Nacional:

• Goalkeeper: Keylor Navas
• Defenders: Pablo Bennevendo, Nathan Silva, Ruben Duarte, Alvaro Angulo
• Midfielders: Jose Caicedo, Santiago Trigos, Pedro Vite, Adalberto Carrasquilla, Jorge Ruvalcaba
• Forward: José Juan Macías

Individual battles, like Macías vs Chivas’ Luis Romo, will likely determine the outcome, making these key players instrumental for Pumas.

Club Universidad Nacional Suspensions & Injuries

Club Universidad Nacional faces a significant hurdle with the absence of their key forward, Guillermo Martinez, who is sidelined with a foot injury and is not expected to return until early January 2026. This absence puts additional pressure on José Juan Macías to deliver in front of the goal.

The good news for Pumas is that there are no suspensions hampering their lineup for this crucial match against Chivas.

However, the absence of Martinez might limit their attacking options, forcing coach Efraín Juárez to rethink his offensive strategies. Backup players will need to step up, and versatile midfielders like Adalberto Carrasquilla could be pushed further forward to fill the attacking void.

Despite this setback, Pumas’ squad depth and tactical flexibility should help them mitigate the impact and put forth a strong performance at home.

Club Universidad Nacional Tactics and Formation

Club Universidad Nacional will likely stick with their familiar 4-2-3-1 formation, designed to optimize both defensive stability and attacking prowess.

Pumas Tactical Breakdown:

• Formation: 4-2-3-1
• Key Forward: José Juan Macías, expected to shoulder the scoring responsibility in Martinez’s absence.
• Midfield Duo: Jose Caicedo and Santiago Trigos provide a solid defensive shield, while Adalberto Carrasquilla will look to dictate play from an advanced midfield position.
• Defensive Strength: Only one clean sheet in their last five matches, indicating room for improvement at the back.
• Notable Strategy: Pumas have a knack for scoring late goals, particularly in the 76-90-minute interval.

With the home crowd at the Estadio Olímpico Universitario behind them, expect Pumas to adopt a high pressing game, looking to capitalize on any defensive lapses from Chivas.

CD Guadalajara Team Analysis

CD Guadalajara Recent Performance WDLWW

CD Guadalajara (Chivas) has demonstrated a competitive edge in their recent fixtures:

• Puebla 0-2 CD Guadalajara (2025-09-27)
• CD Guadalajara 3-1 Necaxa (2025-09-24)
• CD Guadalajara 0-3 Toluca (2025-09-21)
• CD Guadalajara 0-0 Tigres (2025-09-18)
• CF America 1-2 CD Guadalajara (2025-09-14)
  Recent Form: WDLWW

Chivas have been relatively strong, boasting three wins and a draw in their last five matches, with one loss against Toluca. They have averaged 1.40 goals per game and managed to keep two clean sheets in this period. The team’s ability to secure victories, particularly away from home, showcases their resilience and tactical astuteness.

Armando Gonzalez’s form will be crucial as they prepare to face Pumas. Chivas will look to maintain their defensive solidity, having conceded an average of 1.6 goals per game this season. The consistency in both attack and defence will be vital for their ambitions in this matchup.

CD Guadalajara Key Players

CD Guadalajara will be relying heavily on their talisman, Armando Gonzalez, who is the team’s top scorer with 5 goals this season. His ability to find the back of the net will be crucial in breaking down Pumas’ defence.

Midfield maestros Erick Gutierrez and Omar Govea will be key in controlling the game’s tempo, providing both defensive support and creative passing to feed the forwards. Gutierrez, however, is doubtful due to a muscle injury, which could impact their midfield stability.

In defense, Luis Romo and Diego Campillo will anchor the backline, tasked with shutting down Pumas’ attacking plays. Romo’s potential duel with José Juan Macías will be one to watch.

Expected lineup for CD Guadalajara:

• Goalkeeper: José Raúl Rangel
• Defenders: Richard Ledezma, Diego Campillo, Luis Francisco Romo, Miguel Tapias, Bryan Gonzalez
• Midfielders: Efrain Álvarez, Erick Gutierrez, Omar Govea, Santiago Sandoval
• Forward: Armando Gonzalez

These key players will need to perform at their best to secure a positive result against Pumas.

CD Guadalajara Suspensions & Injuries

CD Guadalajara is grappling with a significant injury list ahead of their matchup against Club Universidad Nacional. Key players are set to miss out:

• Leonardo Sepúlveda: Ankle injury, doubtful return.
• Daniel Aguirre: Knock injury, doubtful return.
• Alan Mozo: Meniscus injury, with a potential return in early December 2025.
• Roberto Alvarado: Ankle injury expected to heal by mid-October 2025.
• Erick Gutierrez: Muscle injury, doubtful return.
• Javier Hernández: Knock injury, doubtful return.

These injuries might affect Chivas’ defensive stability and midfield control, challenging coach Gabriel Milito to find optimal replacements. While Armando Gonzalez and the backline remain intact, the absence of key midfielders could hinder their ability to control play and maintain solidity. This presents an added challenge for Chivas as they look to secure points away from home.

CD Guadalajara Tactics and Formation

CD Guadalajara will likely adopt a 5-4-1 formation under coach Gabriel Milito, focusing on defensive solidity while utilizing swift counter-attacks to create scoring opportunities.

Chivas Tactical Breakdown:

• Formation: 5-4-1
• Key Forward: Armando Gonzalez, their leading scorer with 5 goals this season.
• Backline Strength: A five-man defense aiming to nullify Pumas’ attacking threats.
• Midfield Configuration: Efrain Álvarez and Omar Govea are crucial for transitioning play from defense to attack.
• Defensive Resilience: Two clean sheets in their last five matches highlight a robust backline.
• Notable Strategy: Chivas often capitalize on opponents’ mistakes, particularly excelling at scoring in the early stages of matches.

Expected lineup for CD Guadalajara:

• Goalkeeper: José Raúl Rangel
• Defenders: Richard Ledezma, Diego Campillo, Luis Francisco Romo, Miguel Tapias, Bryan Gonzalez
• Midfielders: Efrain Álvarez, Erick Gutierrez, Omar Govea, Santiago Sandoval
• Forward: Armando Gonzalez

This tactical approach will be crucial in containing Pumas’ strong home attack while exploiting counter-attack opportunities.

Club Universidad Nacional vs CD Guadalajara Head-to-Head Statistics

Delving into the recent head-to-head clashes between Club Universidad Nacional (Pumas) and CD Guadalajara (Chivas) provides an intriguing backdrop for this Liga MX encounter. Over the last five meetings, both teams have shared victories and draws, indicating how closely matched they are:

• 2025-03-02, Liga MX Clausura: Club Universidad Nacional 0-1 CD Guadalajara
• 2024-11-03, Liga MX Apertura: CD Guadalajara 0-0 Club Universidad Nacional
• 2024-02-25, Liga MX Clausura: CD Guadalajara 3-1 Club Universidad Nacional
• 2023-12-04, Liga MX Apertura Playoff: Club Universidad Nacional 3-0 CD Guadalajara
• 2023-12-01, Liga MX Apertura Playoff: CD Guadalajara 1-0 Club Universidad Nacional

Recent clashes have seen Chivas edge out Pumas on a few occasions, notably a narrow 1-0 win in their last meeting in March 2025. However, Pumas’ dominant 3-0 win in the 2023 Apertura Playoff highlights their potential when everything clicks.

With both teams aiming to improve their standings, expect a fiercely contested match. The head-to-head history suggests a tight game, but Pumas’ home advantage could be the pivotal factor this time around.

Odds accurate as of 04.10.2025 02:01, and are subject to change. Please always check the odds before placing your bets with any bookmaker.