Puebla vs. CD Guadalajara Prediction, Match Preview and Betting Tips, 27 September 2025

Puebla will host CD Guadalajara at Estadio Cuauhtémoc on 27 September 2025 in the Liga MX. CD Guadalajara, currently sitting 11th on the table, aims to capitalize on Puebla’s recent poor form. Puebla, languishing at the bottom in 18th place, haven’t won in their last 7 league matches.

Despite being the bookmaker’s favorite, CD Guadalajara will need to navigate their injury list to secure a crucial away win. Their current form suggests they are capable, having won 3 out of their last 5 encounters with Puebla. Key scorer Armando Gonzalez, with 5 goals, will be pivotal.

Puebla has their work cut out, especially with top scorer Emiliano Gomez providing a glimmer of hope in an otherwise challenging season. Given the odds and recent performances, our recommended bet is a win for CD Guadalajara. With both teams favoring late-game goals, an exciting finish could be on the cards.

Make sure to tune in for what promises to be an intriguing Liga MX showdown!

Puebla vs CD Guadalajara Prediction & Betting tip

• Team Form and Standing: CD Guadalajara is currently in better form and sits 11th in the table, compared to Puebla’s 18th place. Puebla has not won any of their last 5 matches.
• Head-to-Head Record: CD Guadalajara has a strong record against Puebla, winning 3 out of their last 5 encounters.
• Defensive Issues: Puebla averages 2.40 goals conceded per match, making their defense highly vulnerable, whereas CD Guadalajara has a more resilient defense.

With these factors in mind, an away win for CD Guadalajara appears to be the most promising bet for this matchup.

Puebla vs CD Guadalajara Odds

For this match between Puebla and CD Guadalajara, the odds favor an away win for CD Guadalajara. With Puebla listed at 3.15 for a win and currently at the bottom of the table, their chances seem slim. A draw is marginally less likely at 3.45, reflecting the bookmakers’ view on the competitive edge of this fixture.

CD Guadalajara, with odds of 2.08 for an away win, are the clear favorites, suggesting a confident performance is expected from them. With these odds, placing a bet on CD Guadalajara to secure a victory appears to be the most prudent choice.

Puebla Team Analysis

Puebla Recent Performance

Puebla’s recent form has been less than stellar, as evident from their last five matches: three losses and two draws. Here’s a closer look at their recent results:

• Puebla 2-2 Pachuca
• Necaxa 1-0 Puebla
• Toluca 3-1 Puebla
• Puebla 2-4 Monterrey
• Club Universidad Nacional 0-0 Puebla

Currently sitting at the bottom of the table in 18th place, Puebla has only managed to accumulate 5 points. Their defensive woes are notable, as they’ve conceded an average of 2.40 goals per match in their last five games, while only scoring 1.00 average goals per match.

Despite their challenges, Puebla has shown resilience late in games, scoring the majority of their goals in the final minutes. However, with just one clean sheet in their last five matches, tightening up their defense will be crucial if they hope to turn their season around.

This analysis suggests that Puebla will need to significantly improve their form if they wish to climb out of the relegation zone.

Puebla Key Players

Puebla’s main hope for an impactful performance will likely rest on the shoulders of their top scorer, Emiliano Gomez, who has netted 3 goals this season. His ability to exploit gaps in CD Guadalajara’s defense will be crucial.

Another key figure is Julio Gonzalez, the goalkeeper, who will need to marshal his defense effectively to stem the tide of goals they’ve been conceding. With an average of 2.2 yellow cards per game, discipline will also be pivotal for Puebla.

Potential key battles include Emiliano Gomez up against CD Guadalajara’s formidable defender Luis Romo, which could very well be the deciding factor in attacking success for Puebla.

While the expected lineup for Puebla hasn’t been confirmed, their recent 4-4-2 formation may see a similar set-up involving:

• Goalkeeper: Julio Gonzalez
• Defenders: Jesus Rivas, Eduardo Navarro, Nicolas Diaz, Fernando Monarrez
• Midfielders: Owen Gonzalez, Franco Moyano, Ariel Gamarra, Emiliano Gomez
• Forwards: Raul Castillo, Ricardo Marin

How these players perform individually and as a unit will determine Puebla’s success in this important clash.

Puebla Suspensions & Injuries

Puebla faces significant challenges with key injuries that could impact their performance against CD Guadalajara. They will be without Fernando Aristeguieta, who is sidelined with a broken foot, and Lucas Cavallini, out with a cruciate ligament injury until late March 2026. Additionally, Juan Fedorco is recovering from a concussion and is expected to return in early October 2025.

The absence of these players puts a strain on Puebla’s squad depth, particularly in attack and midfield, reducing their options for tactical flexibility. These injuries could force coach changes to the lineup, potentially weakening their already struggling defense and limiting their offensive firepower. With such critical players missing, Puebla will have to dig deep to find a way to counter CD Guadalajara’s strengths.

Puebla Tactics and Formation

Puebla Tactical Breakdown:

• Formation: 4-4-2 (Recent 4-4-2 formation is likely to be used)
• Key Forward: Emiliano Gomez (Top scorer with 3 goals)
• Midfield Engine: Ariel Gamarra, Owen Gonzalez, Franco Moyano
• Defensive Challenges: Only one clean sheet in the last five matches, conceding 2.40 goals per game.
• Notable Strategy: Puebla tends to score most of their goals in the 76–90 minute interval, indicating a strong finish to their games.

Given their defensive struggles, Puebla will need to balance their tactics, tightening up at the back while trying to exploit CD Guadalajara’s vulnerabilities in the latter stages of the match. The anticipated 4-4-2 formation will require solid coordination between the midfield and defense to stand a chance against a more in-form opponent.

CD Guadalajara Team Analysis

CD Guadalajara Recent Performance

CD Guadalajara’s form has been a mixed bag in their last five matches, securing two wins, one draw, and two losses. Here’s a breakdown of their recent results:

• CD Guadalajara 3-1 Necaxa
• CD Guadalajara 0-3 Toluca
• CD Guadalajara 0-0 Tigres
• CF America 1-2 CD Guadalajara
• CD Guadalajara 1-2 Cruz Azul

Currently in 11th place with 14 points, CD Guadalajara has managed an average of 1.20 goals per match over the last five fixtures and maintained one clean sheet during this period. Relevant details show they are capable of putting up a fight and achieving crucial results, even on the road.

While their defense hasn’t been impenetrable, conceding around 1.4 goals per game, their attack led by top scorer Armando Gonzalez has the capability to exploit Puebla’s defensive frailties. If they maintain consistency and capitalize on key moments, Guadalajara is poised for a strong performance.

CD Guadalajara Key Players

CD Guadalajara will rely heavily on their top scorer Armando Gonzalez, who has netted 5 goals this season, to lead their attack. His finishing ability and knack for scoring late in games could be vital, especially against a Puebla defense that tends to concede frequently.

In midfield, Richard Ledezma’s creativity and Miguel Gomez’s work rate will be crucial in breaking down Puebla’s lines. Defensively, the robust presence of Luis Romo will look to keep Puebla’s attacking threats at bay, making for an interesting duel against Puebla’s Emiliano Gomez.

Here’s the expected lineup for CD Guadalajara:

• Goalkeeper: Jose Rangel
• Defenders: Jose Castillo, Luis Romo, Bryan Gonzalez
• Midfielders: Omar Govea, Miguel Gomez, Diego Campillo, Richard Ledezma, Efrain Alvarez
• Forwards: Armando Gonzalez, Santiago Sandoval

This blend of seasoned defenders and dynamic attackers makes CD Guadalajara a well-rounded and formidable side for this encounter.

CD Guadalajara Suspensions & Injuries

CD Guadalajara’s lineup for their clash against Puebla will be significantly impacted by injuries. Leonardo Sepúlveda (ankle injury) and Roberto Alvarado (ankle injury) are both sidelined and expected back in early October 2025. Meanwhile, Alan Mozo will be out until early December 2025 due to a meniscus injury. There are also doubts concerning Daniel Aguirre (knock injury) and Erick Gutierrez (muscle injury), making their participation uncertain.

These injuries could limit Guadalajara’s bench strength and their ability to maintain tactical flexibility during the match. The absence of pivotal players like Alvarado, known for his creativity, will particularly strain their offensive capabilities. However, with a depth of talent in their squad, Guadalajara still has the potential to cope with these setbacks effectively.

CD Guadalajara Tactics and Formation

CD Guadalajara Tactical Breakdown:

• Formation: 3-1-4-2 (Expected to continue with this formation from recent matches)
• Key Forward: Armando Gonzalez (Top scorer with 5 goals)
• Midfield Engine: Richard Ledezma, Miguel Gomez, Efrain Alvarez
• Defensive Set-Up: Featuring a back three led by Luis Romo
• Notable Strategy: CD Guadalajara often scores most of their goals late in games, particularly in the 76–90 minute interval

Guadalajara will likely rely on their 3-1-4-2 formation, with a focus on maintaining possession and creating scoring opportunities through their midfield dynamism and wide attacks. The defensive trio, reinforced by a holding midfielder, aims to nullify Puebla’s offensive strategies while transitioning quickly to counter-attacks. This balanced approach is designed to exploit Puebla’s defensive vulnerabilities, particularly in the latter stages of the match.

Puebla vs CD Guadalajara Head-to-Head Statistics

In their last five encounters, CD Guadalajara holds a slight advantage over Puebla:

• 16 April 2025: CD Guadalajara 1-0 Puebla
• 26 October 2024: Puebla 1-0 CD Guadalajara
• 7 April 2024: CD Guadalajara 3-2 Puebla
• 21 October 2023: Puebla 0-2 CD Guadalajara
• 11 March 2023: Puebla 1-0 CD Guadalajara

Overall, CD Guadalajara has won 3 out of these 5 meetings, while Puebla managed to win 2. This shows that matches between these two teams can often be tightly contested.

The most recent encounter saw CD Guadalajara clinch a narrow 1-0 victory, which could give them a psychological edge heading into this fixture. However, Puebla did triumph 1-0 the last time these two met at Estadio Cuauhtémoc, suggesting home advantage could be crucial.

Given these head-to-head statistics, this matchup promises to be an intriguing fixture with potential for a close contest.

Odds accurate as of 25/09/2025 04:04, and are subject to change. Please always check the odds before placing your bets with any bookmaker.