American football | Friday, September 16, 2022 10:36 AM (Revised at: Saturday, September 17, 2022 8:19 AM)

NFL Week 2 Best Bets: Two Standout Wagers For Week 2

NFL Week 2 Best Bets: Two Standout Wagers For Week 2
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NFL Week 2 Best Bets: Sunday, September 18th

Week 2 of the NFL season kicked off on Thursday night with the Kansas City Chiefs getting the better of the Los Angeles Chargers. Kansas City is the first team to 2-0, but how many other franchises will join them by the time Week 2 is wrapped up?

After the usual tsunami of hot takes from Week 1, we have dived into the betting markets to identify our best bets for the second round of games. Let’s start off in north California with an NFC West matchup.

In this article:


San Francisco 49ers vs Seattle Seahawks Preview

Sun, Sep 18. 21:05 (UK time)

The San Francisco 49ers lost as favourites to the Chicago Bears in Week 1. George Kittle seems unlikely to play in this game too, and Trey Lance did nothing in the season opener to win over his sceptics. San Francisco’s defence was as advertised, but Lance generated just 10 points of offence, and another challenging game is expected even against the rebuilding Seahawks.

Seattle was on the other side of an upset, moving to 1-0 with a surprise win over the Denver Broncos. The defence forced a couple of turnovers, and Geno Smith was impressive in his efficiency. While Russell Wilson and others have departed, it is worth noting that the Seahawks have won the last four against the Niners, and they are full of confidence coming into this one. They have some of their own injury concerns, however, which makes the moneyline unappealing.


San Francisco 49ers vs Seattle Seahawks Best Bet

Being 7.5-point underdogs feels harsh on the Seahawks. Of course, only so much can be read into Week 1, but at the same time, the failings of the Niners were not exactly a surprise. Kittle’s absence makes Lance’s life that much harder.

The Seahawks may still lose on their trip south, yet they are good value to at least keep this within a touchdown.

  • Selection: Seattle Seahawks +7.5
  • Best Odds: 2.11 (Pinnacle)
  • Stakes: 6/10

Odds as at 10:00 am on September 16th, 2022. Odds may now differ.

More San Francisco 49ers vs Seattle Seahawks Tips


Detroit Lions vs Washington Commanders Preview

Sun, Sep 18. 18:00 (UK time)

Washington had to fight hard to beat the Jacksonville Jaguars in Week 1. Carson Wentz was typically inconsistent, recording four passing touchdowns but also giving the ball away twice.

Detroit pushed the Philadelphia Eagles all the way in a 38-35 thriller. Their stock rose despite the loss, with Jared Goff exhibiting his game management skills, and D’Andre Swift producing throughout. Swift is expected to play despite an ankle injury – he’s a big factor here after the Commanders allowed over 100 yards on the ground to James Robinson and Travis Etienne.

Despite Washington winning and Detroit losing in Week 1, the respective performances made it feel like the opposite outcomes. The Commanders are clearly a flawed team, short on elite talent. Detroit is going to fight hard all year long, and has some top-end players on its roster. Time will tell whether that’s enough for a playoff push, but for now, the Lions are a difficult opponent, particularly with homefield advantage.


Detroit Lions vs Washington Commanders Best Bet

The Lions are only narrowly favoured for this game. On paper, these teams are pretty much even. Throw in the homefield, and the Lions should really be a shorter price than this. There’s value in backing Detroit to win.

  • Selection: Detroit Lions Moneyline
  • Best Odds: 1.90 (Coolbet)
  • Stakes: 4/10

Odds as at 10:00 am on September 16th, 2022. Odds may now differ.

More Detroit Lions vs Washington Commanders Tips


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